The aim of this study was to formulate skincare products utilizing a new coating applied to zinc oxide and titanium dioxide particles and complementary skincare ingredients to provide broad protection against a range of environmental insults
Eric F. Bernstein MD, MSE, Harry W. Sarkas, PhD, Patrica Boland, BA, and Deborah Bouche
Premature skin aging results from exposure to a range of environmental factors, primarily ultraviolet radiation, but also high-energy visible light in the blue spectrum, infrared radiation, and environmental pollution.
These extrinsic factors result in the generation of reactive oxygen species which promote photoaging and DNA damage resulting in skin cancers. Colorescience formulated skincare products utilizing a new coating applied to zinc oxide and titanium dioxide particles and complimentary skincare ingredients to provide broad protection against a range of environmental insults.
When applied as a topical formulation, multifunctional coating on zinc oxide particles resulted in a 245% reduction in the number of free radicals generated in the skin following UV exposure
The antioxidant boosting effect of multifunctional‐coated zinc oxide is substantially greater than single‐coated zinc oxide
Free radical assays of commercial face lotion emulsion sunscreen formulas following UV radiation exposure. The formula described in this work, incorporating multifunctional‐coated mineral UV filters and selected antioxidants, greatly outperforms the competitor formulas
Results: A series of in vitro and ex vivo studies demonstrated the ability of mineral-based products formulated with the new multifunctional coating to provide protection against ultraviolet radiation, high-energy visible light, infrared radiation, and environmental pollution.
Conclusion: Newly formulated mineral-based skincare products provide environmental protection, are ecologically safe, and can replace chemical-based sunscreen ingredients.
