A novel topical cream was developed to address the appearance of aging periorbital skin. The goal of this study was to evaluate the efficacy and tolerability of this product (Total Eye® Firm & Repair Cream; Colorescience, Inc., Carlsbad, CA) for improving periorbital wrinkles, dryness, laxity, and dark circles.
Efficacy and tolerability of a novel skin cream for improving periocular rhytids and dryness
Jacqueline M. Calkin MD, Alison A. Boudreaux MD, and Barbara Taylor BA
This 8-week study evaluated a topical cream designed to improve signs of aging around the eyes, including wrinkles, dryness, and dark circles. All participants showed improvement by weeks 4 and 8, half achieving moderate or marked improvement.
The product was well-tolerated, and most subjects reported feeling more hydrated, healthier, and confident in their appearance.
A novel topical cream has been developed for the treatment of periorbital wrinkles, dryness, laxity, and dark circles. When applied twice-daily for 8 weeks, study investigators reported significant improvements in wrinkles, dryness and laxity at Week 4 and all parameters at Week 8.
82%
of subjects who had concerns about firmness and laxity experienced improvement
87%
of subjects who had concerns about lines and wrinkles agreed they experienced improvement.
Baseline (left) and after 8 weeks of treatment (right)
82%
of subjects who had concerns about firmness and laxity experienced improvement
87%
of subjects who had concerns about lines and wrinkles agreed they experienced improvement.
Baseline (left) and after 8 weeks of treatment (right)
82%
of subjects who had concerns about firmness and laxity experienced improvement
87%
of subjects who had concerns about lines and wrinkles agreed they experienced improvement.
Baseline (left) and after 8 weeks of treatment (right)
100%
agreed that the product made their eyes feel more hydrated
95%
look and feel healthier
91%
increased confidence in their eye appearance
Twice-daily Total Eye® Firm & Repair Cream improved the overall appearance of the periorbital area. The product was well-tolerated and most treated subjects were satisfied with their results. The product is a viable option for treating periorbital wrinkles and laxity and should be considered a safe and effective skincare option.
See what the experts are saying
As investigators for the Colorescience® Total Eye Firm & Repair Cream clinical study, both Dr. Boudreaux and I were able to observe and measure firsthand the multiple benefits of this product. We were particularly impressed to see improvement in laxity, especially in the upper eyelids, and dryness as early as 4 weeks and pleased that 100% of subjects showed global improvement by week 8. Total Eye® Firm & Repair Cream perfectly complements the Total Eye® collection and has quickly become a patient favorite.
Jacqueline M. Calkin, MD,
Calking & Boudreaux Dermatology, a Golden State Dermatology Affiliate, Sacramento, CA
